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BCR Selection and Affinity Maturation in Peyer’s Patches Germinal Centers
Antigen-binding B cell receptor (BCR)/antibody variable regions are encoded by exons assembled in developing B cells by V(D)J recombination(1). Immensely diverse primary BCR repertoires derive from mechanisms that diversify V(D)J gene segment junctions that contribute to the antigen contact compleme...
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| Publié dans: | Nature |
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| Auteurs principaux: | , , , , , , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2020
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7478071/ https://ncbi.nlm.nih.gov/pubmed/32499646 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41586-020-2262-4 |
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