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TIGIT in cancer immunotherapy

Tumors evade immune-mediated recognition through multiple mechanisms of immune escape. On chronic tumor antigen exposure, T cells become dysfunctional/exhausted and upregulate various checkpoint inhibitory receptors (IRs) that limit T cells’ survival and function. During the last decade, immunothera...

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Bibliografische gegevens
Gepubliceerd in:J Immunother Cancer
Hoofdauteurs: Chauvin, Joe-Marc, Zarour, Hassane M
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: BMJ Publishing Group 2020
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7477968/
https://ncbi.nlm.nih.gov/pubmed/32900861
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/jitc-2020-000957
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