Effects of paracetamol (acetaminophen) on gene expression and permeability properties of the rat placenta and fetal brain

Background: Paracetamol (acetaminophen) is widely used in pregnancy and generally regarded as “safe” by regulatory authorities. Methods: Clinically relevant doses of paracetamol were administered intraperitoneally to pregnant rats twice daily from embryonic day E15 to 19 (chronic) or as a single dos...

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Udgivet i:F1000Res
Main Authors: Koehn, Liam M., Huang, Yifan, Habgood, Mark D, Kysenius, Kai, Crouch, Peter J., Dziegielewska, Katarzyna M, Saunders, Norman R
Format: Artigo
Sprog:Inglês
Udgivet: F1000 Research Limited 2020
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7477648/
https://ncbi.nlm.nih.gov/pubmed/32934805
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.12688/f1000research.24119.2
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