Activation of autophagy inhibits nucleotide‐binding oligomerization domain‐like receptor protein 3 inflammasome activation and attenuates myocardial ischemia‐reperfusion injury in diabetic rats

AIMS/INTRODUCTION: Diabetic hearts are more vulnerable to ischemia‐reperfusion injury (I/RI). The activation of nucleotide‐binding oligomerization domain‐like receptor protein 3 (NLRP3) inflammasome can mediate the inflammatory process, and hence might contribute to myocardial I/RI. Activation of au...

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Publicado en:J Diabetes Investig
Autores principales: Zhang, Dengwen, He, Yi, Ye, Xiaodong, Cai, Yin, Xu, Jindong, Zhang, Liangqing, Li, Mingyi, Liu, Hao, Wang, Sheng, Xia, Zhengyuan
Formato: Artigo
Lenguaje:Inglês
Publicado: John Wiley and Sons Inc. 2020
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Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7477534/
https://ncbi.nlm.nih.gov/pubmed/32064785
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jdi.13235
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