N-Acetylcysteine Attenuates Diabetic Myocardial Ischemia Reperfusion Injury through Inhibiting Excessive Autophagy

Background. Excessive autophagy is a major mechanism of myocardial ischemia reperfusion injury (I/RI) in diabetes with enhanced oxidative stress. Antioxidant N-acetylcysteine (NAC) reduces myocardial I/RI. It is unknown if inhibition of autophagy may represent a mechanism whereby NAC confers cardiop...

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Detalhes bibliográficos
Publicado no:Mediators Inflamm
Main Authors: Wang, Sheng, Wang, Chunyan, Yan, Fuxia, Wang, Tingting, He, Yi, Li, Haobo, Xia, Zhengyuan, Zhang, Zhongjun
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2017
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5317145/
https://ncbi.nlm.nih.gov/pubmed/28265179
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2017/9257291
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