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TRPV6 calcium channel directs homeostasis of the mammary epithelial sheets and controls epithelial mesenchymal transition

Epithelial integrity is lost upon cancer progression as cancer cells detach from the primary tumor site and start to invade to the surrounding tissues. Invasive cancers of epithelial origin often express altered levels of TRP-family cation channels. Upregulation of TRPV6 Ca(2+)-channel has been asso...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Kärki, Tytti, Rajakylä, Eeva Kaisa, Acheva, Anna, Tojkander, Sari
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7477193/
https://ncbi.nlm.nih.gov/pubmed/32895467
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-71645-z
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