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TRPV6 calcium channel directs homeostasis of the mammary epithelial sheets and controls epithelial mesenchymal transition

Epithelial integrity is lost upon cancer progression as cancer cells detach from the primary tumor site and start to invade to the surrounding tissues. Invasive cancers of epithelial origin often express altered levels of TRP-family cation channels. Upregulation of TRPV6 Ca(2+)-channel has been asso...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Sci Rep
Hauptverfasser: Kärki, Tytti, Rajakylä, Eeva Kaisa, Acheva, Anna, Tojkander, Sari
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7477193/
https://ncbi.nlm.nih.gov/pubmed/32895467
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-71645-z
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