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Ozone-derived oxysterols impair lung macrophage phagocytosis via adduction of some phagocytosis receptors
Inhalation of the ambient air pollutant ozone causes lung inflammation and can suppress host defense mechanisms, including impairing macrophage phagocytosis. Ozone reacts with cholesterol in the lung to form oxysterols, like secosterol A and secosterol B (SecoA and SecoB), which can form covalent ad...
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| Pubblicato in: | J Biol Chem |
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| Autori principali: | , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Society for Biochemistry and Molecular Biology
2020
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7476716/ https://ncbi.nlm.nih.gov/pubmed/32690608 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA120.013699 |
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