Ozone-derived Oxysterols Affect Liver X Receptor (LXR) Signaling: A POTENTIAL ROLE FOR LIPID-PROTEIN ADDUCTS

When inhaled, ozone (O(3)) interacts with cholesterols of airway epithelial cell membranes or the lung-lining fluid, generating chemically reactive oxysterols. The mechanism by which O(3)-derived oxysterols affect molecular function is unknown. Our data show that in vitro exposure of human bronchial...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Speen, Adam M., Kim, Hye-Young H., Bauer, Rebecca N., Meyer, Megan, Gowdy, Kymberly M., Fessler, Michael B., Duncan, Kelly E., Liu, Wei, Porter, Ned A., Jaspers, Ilona
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2016
Assuntos:
Lipids
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5122785/
https://ncbi.nlm.nih.gov/pubmed/27703007
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.732362
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