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Berberine alleviates cisplatin-induced acute kidney injury by regulating mitophagy via PINK 1/Parkin pathway

BACKGROUND: To study the protective effect of berberine (BBR) on cisplatin-induced acute kidney injury (AKI) and its effect on mitophagy. METHODS: (I) Male C57BL/6 mice aged 6–8 weeks were randomly divided into control group (saline), cisplatin group (cisplatin), and cisplatin + BBR (5, 10 mg/kg) gr...

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Bibliografske podrobnosti
izdano v:Transl Androl Urol
Main Authors: Qi, Jieying, Xue, Qi, Kuang, Liuyan, Xie, Lifen, Luo, Ren, Nie, Xiaoli
Format: Artigo
Jezik:Inglês
Izdano: AME Publishing Company 2020
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7475663/
https://ncbi.nlm.nih.gov/pubmed/32944532
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.21037/tau-20-1129
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