Llwytho...

Indoles from the commensal microbiota act via the AHR and IL-10 to tune the cellular composition of the colonic epithelium during aging

The intestinal epithelium is a highly dynamic structure that rejuvenates in response to acute stressors and can undergo alterations in cellular composition as animals age. The microbiota, acting via secreted factors related to indole, appear to regulate the sensitivity of the epithelium to stressors...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Proc Natl Acad Sci U S A
Prif Awduron: Powell, Domonica N., Swimm, Alyson, Sonowal, Robert, Bretin, Alexis, Gewirtz, Andrew T., Jones, Rheinallt M., Kalman, Daniel
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: National Academy of Sciences 2020
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7474656/
https://ncbi.nlm.nih.gov/pubmed/32817517
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2003004117
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