Global epigenomic analysis of KSHV-infected primary effusion lymphoma identifies functional MYC superenhancers and enhancer RNAs

Enhancers play indispensable roles in cell proliferation and survival through spatiotemporally regulating gene transcription. Active enhancers and superenhancers often produce noncoding enhancer RNAs (eRNAs) that precisely control RNA polymerase II activity. Kaposi’s sarcoma-associated herpesvirus (...

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Bibliografiske detaljer
Udgivet i:Proc Natl Acad Sci U S A
Main Authors: Park, Angela, Oh, Soohwan, Jung, Kyle L., Choi, Un Yung, Lee, Hye-Ra, Rosenfeld, Michael G., Jung, Jae U.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2020
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7474655/
https://ncbi.nlm.nih.gov/pubmed/32817485
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1922216117
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