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Global epigenomic analysis of KSHV-infected primary effusion lymphoma identifies functional MYC superenhancers and enhancer RNAs

Enhancers play indispensable roles in cell proliferation and survival through spatiotemporally regulating gene transcription. Active enhancers and superenhancers often produce noncoding enhancer RNAs (eRNAs) that precisely control RNA polymerase II activity. Kaposi’s sarcoma-associated herpesvirus (...

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Bibliografski detalji
Izdano u:Proc Natl Acad Sci U S A
Glavni autori: Park, Angela, Oh, Soohwan, Jung, Kyle L., Choi, Un Yung, Lee, Hye-Ra, Rosenfeld, Michael G., Jung, Jae U.
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2020
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7474655/
https://ncbi.nlm.nih.gov/pubmed/32817485
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1922216117
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