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Global epigenomic analysis of KSHV-infected primary effusion lymphoma identifies functional MYC superenhancers and enhancer RNAs

Enhancers play indispensable roles in cell proliferation and survival through spatiotemporally regulating gene transcription. Active enhancers and superenhancers often produce noncoding enhancer RNAs (eRNAs) that precisely control RNA polymerase II activity. Kaposi’s sarcoma-associated herpesvirus (...

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Bibliografische gegevens
Gepubliceerd in:Proc Natl Acad Sci U S A
Hoofdauteurs: Park, Angela, Oh, Soohwan, Jung, Kyle L., Choi, Un Yung, Lee, Hye-Ra, Rosenfeld, Michael G., Jung, Jae U.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: National Academy of Sciences 2020
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7474655/
https://ncbi.nlm.nih.gov/pubmed/32817485
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1922216117
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