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Global epigenomic analysis of KSHV-infected primary effusion lymphoma identifies functional MYC superenhancers and enhancer RNAs

Enhancers play indispensable roles in cell proliferation and survival through spatiotemporally regulating gene transcription. Active enhancers and superenhancers often produce noncoding enhancer RNAs (eRNAs) that precisely control RNA polymerase II activity. Kaposi’s sarcoma-associated herpesvirus (...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Park, Angela, Oh, Soohwan, Jung, Kyle L., Choi, Un Yung, Lee, Hye-Ra, Rosenfeld, Michael G., Jung, Jae U.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7474655/
https://ncbi.nlm.nih.gov/pubmed/32817485
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1922216117
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