mRNA adenosine methylase (MTA) deposits m(6)A on pri-miRNAs to modulate miRNA biogenesis in Arabidopsis thaliana

In Arabidopsis thaliana, the METTL3 homolog, mRNA adenosine methylase (MTA) introduces N(6)-methyladenosine (m(6)A) into various coding and noncoding RNAs of the plant transcriptome. Here, we show that an MTA-deficient mutant (mta) has decreased levels of microRNAs (miRNAs) but accumulates primary m...

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Detaylı Bibliyografya
Yayımlandı:Proc Natl Acad Sci U S A
Asıl Yazarlar: Bhat, Susheel Sagar, Bielewicz, Dawid, Gulanicz, Tomasz, Bodi, Zsuzsanna, Yu, Xiang, Anderson, Stephen J., Szewc, Lukasz, Bajczyk, Mateusz, Dolata, Jakub, Grzelak, Natalia, Smolinski, Dariusz J., Gregory, Brian D., Fray, Rupert G., Jarmolowski, Artur, Szweykowska-Kulinska, Zofia
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: National Academy of Sciences 2020
Konular:
Biological Sciences
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7474595/
https://ncbi.nlm.nih.gov/pubmed/32817553
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2003733117
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