mRNA adenosine methylase (MTA) deposits m(6)A on pri-miRNAs to modulate miRNA biogenesis in Arabidopsis thaliana

In Arabidopsis thaliana, the METTL3 homolog, mRNA adenosine methylase (MTA) introduces N(6)-methyladenosine (m(6)A) into various coding and noncoding RNAs of the plant transcriptome. Here, we show that an MTA-deficient mutant (mta) has decreased levels of microRNAs (miRNAs) but accumulates primary m...

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Bibliografiska uppgifter
I publikationen:Proc Natl Acad Sci U S A
Huvudupphovsmän: Bhat, Susheel Sagar, Bielewicz, Dawid, Gulanicz, Tomasz, Bodi, Zsuzsanna, Yu, Xiang, Anderson, Stephen J., Szewc, Lukasz, Bajczyk, Mateusz, Dolata, Jakub, Grzelak, Natalia, Smolinski, Dariusz J., Gregory, Brian D., Fray, Rupert G., Jarmolowski, Artur, Szweykowska-Kulinska, Zofia
Materialtyp: Artigo
Språk:Inglês
Publicerad: National Academy of Sciences 2020
Ämnen:
Biological Sciences
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC7474595/
https://ncbi.nlm.nih.gov/pubmed/32817553
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2003733117
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