EGCG Attenuates Renal Damage via Reversing Klotho Hypermethylation in Diabetic db/db Mice and HK-2 Cells

To explore whether epigallocatechin-3-gallate (EGCG) improves renal damage in diabetic db/db mice and high-glucose- (HG-) induced injury in HK-2 cells by regulating the level of Klotho gene promoter methylation. Western blotting was used to detect the protein expression levels of DNA methyltransfera...

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Vydáno v:Oxid Med Cell Longev
Hlavní autoři: Yang, Xiu Hong, Zhang, Bao Long, Zhang, Xiao Meng, Tong, Jin Dong, Gu, Yan Hong, Guo, Li Li, Jin, Hui Min
Médium: Artigo
Jazyk:Inglês
Vydáno: Hindawi 2020
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7474393/
https://ncbi.nlm.nih.gov/pubmed/32908633
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2020/6092715
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