Both Boceprevir and GC376 efficaciously inhibit SARS-CoV-2 by targeting its main protease

COVID-19 was declared a pandemic on March 11 by WHO, due to its great threat to global public health. The coronavirus main protease (M(pro), also called 3CLpro) is essential for processing and maturation of the viral polyprotein, therefore recognized as an attractive drug target. Here we show that a...

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Publicado no:Nat Commun
Main Authors: Fu, Lifeng, Ye, Fei, Feng, Yong, Yu, Feng, Wang, Qisheng, Wu, Yan, Zhao, Cheng, Sun, Huan, Huang, Baoying, Niu, Peihua, Song, Hao, Shi, Yi, Li, Xuebing, Tan, Wenjie, Qi, Jianxun, Gao, George Fu
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7474075/
https://ncbi.nlm.nih.gov/pubmed/32887884
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-18233-x
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