Conditional Deletion of PGC-1α Results in Energetic and Functional Defects in NK Cells

During an immune response, natural killer (NK) cells activate specific metabolic pathways to meet the increased energetic and biosynthetic demands associated with effector functions. Here, we found in vivo activation of NK cells during Listeria monocytogenes infection-augmented transcription of gene...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:iScience
Päätekijät: Gerbec, Zachary J., Hashemi, Elaheh, Nanbakhsh, Arash, Holzhauer, Sandra, Yang, Chao, Mei, Ao, Tsaih, Shirng-Wern, Lemke, Angela, Flister, Michael J., Riese, Matthew J., Thakar, Monica S., Malarkannan, Subramaniam
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Elsevier 2020
Aiheet:
Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC7474003/
https://ncbi.nlm.nih.gov/pubmed/32858341
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.isci.2020.101454
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