Llgl1 regulates zebrafish cardiac development by mediating Yap stability in cardiomyocytes

The Hippo-Yap pathway regulates multiple cellular processes in response to mechanical and other stimuli. In Drosophila, the polarity protein Lethal (2) giant larvae [L(2)gl], negatively regulates Hippo-mediated transcriptional output. However, in vertebrates, little is known about its homolog Llgl1....

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Detalhes bibliográficos
Publicado no:Development
Main Authors: Flinn, Michael A., Otten, Cécile, Brandt, Zachary J., Bostrom, Jonathan R., Kenarsary, Aria, Wan, Tina C., Auchampach, John A., Abdelilah-Seyfried, Salim, O'Meara, Caitlin C., Link, Brian A.
Formato: Artigo
Idioma:Inglês
Publicado em: The Company of Biologists Ltd 2020
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7473637/
https://ncbi.nlm.nih.gov/pubmed/32843528
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.193581
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