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Heg1 and Ccm1/2 proteins control endocardial mechanosensitivity during zebrafish valvulogenesis

Endothelial cells respond to different levels of fluid shear stress through adaptations of their mechanosensitivity. Currently, we lack a good understanding of how this contributes to sculpting of the cardiovascular system. Cerebral cavernous malformation (CCM) is an inherited vascular disease that...

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Detalhes bibliográficos
Publicado no:eLife
Main Authors: Donat, Stefan, Lourenço, Marta, Paolini, Alessio, Otten, Cécile, Renz, Marc, Abdelilah-Seyfried, Salim
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5794256/
https://ncbi.nlm.nih.gov/pubmed/29364115
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.28939
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