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Gluconeogenesis and PEPCK are critical components of healthy aging and dietary restriction life extension

High glucose diets are unhealthy, although the mechanisms by which elevated glucose is harmful to whole animal physiology are not well understood. In Caenorhabditis elegans, high glucose shortens lifespan, while chemically inflicted glucose restriction promotes longevity. We investigated the impact...

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Bibliografiska uppgifter
I publikationen:PLoS Genet
Huvudupphovsmän: Onken, Brian, Kalinava, Natallia, Driscoll, Monica
Materialtyp: Artigo
Språk:Inglês
Publicerad: Public Library of Science 2020
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC7473531/
https://ncbi.nlm.nih.gov/pubmed/32841230
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1008982
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