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Gluconeogenesis and PEPCK are critical components of healthy aging and dietary restriction life extension

High glucose diets are unhealthy, although the mechanisms by which elevated glucose is harmful to whole animal physiology are not well understood. In Caenorhabditis elegans, high glucose shortens lifespan, while chemically inflicted glucose restriction promotes longevity. We investigated the impact...

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Detalhes bibliográficos
Publicado no:PLoS Genet
Main Authors: Onken, Brian, Kalinava, Natallia, Driscoll, Monica
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7473531/
https://ncbi.nlm.nih.gov/pubmed/32841230
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1008982
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