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Regulation of T cell receptor signaling by protein acyltransferase DHHC21

S-acylation – reversible post-translational lipidation of cysteine residues – is emerging as an important regulatory mechanism in T cell signaling. Dynamic S-acylation is critical for protein recruitment into the T cell receptor complex and initiation of the subsequent signaling cascade. However, th...

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Bibliographische Detailangaben
Veröffentlicht in:Mol Biol Rep
Hauptverfasser: Fan, Ying, Shayahati, Bieerkehazhi, Tewari, Ritika, Boehning, Darren, Akimzhanov, Askar M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7473483/
https://ncbi.nlm.nih.gov/pubmed/32789573
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11033-020-05691-1
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