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RNA-dependent RNA polymerase: Structure, mechanism, and drug discovery for COVID-19

Coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) has rapidly become a global pandemic. Although great efforts have been made to develop effective therapeutic interventions, only the nucleotide analog remdesivir was approved for emergency use...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Biochem Biophys Res Commun
Hauptverfasser: Jiang, Yi, Yin, Wanchao, Xu, H. Eric
Format: Artigo
Sprache:Inglês
Veröffentlicht: Elsevier Inc. 2021
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7473028/
https://ncbi.nlm.nih.gov/pubmed/32943188
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2020.08.116
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