Indomethacin Increases the Efficacy of Oxygen Utilization of Colonic Mitochondria and Uncouples Hepatic Mitochondria in Tissue Homogenates From Healthy Rats

Background: Studies suggest that indomethacin (Indo) exhibits detrimental changes in the small intestine (microvascular disorder, villus shortening, and epithelial disruption), mainly due to mitochondrial uncoupling. The effects of Indo on colon and liver tissue are unclear. The aim of this study wa...

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Detalhes bibliográficos
Publicado no:Front Med (Lausanne)
Main Authors: Herminghaus, Anna, Buitenhuis, Albert J., Schulz, Jan, Truse, Richard, Vollmer, Christian, Relja, Borna, Bauer, Inge, Picker, Olaf
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Medicine
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7472952/
https://ncbi.nlm.nih.gov/pubmed/32974368
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmed.2020.00463
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