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Nitroglycerin and Iloprost Improve Mitochondrial Function in Colon Homogenate Without Altering the Barrier Integrity of Caco-2 Monolayers

Locally applied nitroglycerin [nitric oxide (NO) donor] and iloprost (analog of prostacyclin PGI(2)) improve regional gastric oxygenation and nitroglycerin preserves gastric mucosal barrier integrity. This suggests direct effects of these substances on oxygenation and barrier function. The aim of th...

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Publicat a:Front Med (Lausanne)
Autors principals: Herminghaus, Anna, Eberhardt, Rebecca, Truse, Richard, Schulz, Jan, Bauer, Inge, Picker, Olaf, Vollmer, Christian
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6232762/
https://ncbi.nlm.nih.gov/pubmed/30460235
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmed.2018.00291
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