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Clinical implications of PTEN loss in prostate cancer
Genomic aberrations of the PTEN tumour suppressor gene are among the most common in prostate cancer. Inactivation of the PTEN gene by deletion or mutation is identified in ~20% of primary prostate tumour samples at radical prostatectomy and as many as 50% of castration resistant tumours. Loss of PTE...
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| Publicado no: | Nat Rev Urol |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7472658/ https://ncbi.nlm.nih.gov/pubmed/29460925 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrurol.2018.9 |
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