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Cytoplasmic PTEN Protein Loss Distinguishes Intraductal Carcinoma of the Prostate from High Grade Prostatic Intraepithelial Neoplasia

Intraductal carcinoma of the prostate is a marker of aggressive disease. However, intraductal carcinoma exists on a morphologic continuum with high grade prostatic intraepithelial carcinoma (PIN) and distinguishing intraductal carcinoma from PIN is a common diagnostic dilemma with significant clinic...

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Detalhes bibliográficos
Main Authors: Lotan, Tamara L., Gumuskaya, Berrak, Rahimi, Hameed, Hicks, Jessica L., Iwata, Tsuyoshi, Robinson, Brian D., Epstein, Jonathan I., De Marzo, Angelo M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3610824/
https://ncbi.nlm.nih.gov/pubmed/23222491
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/modpathol.2012.201
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