The angiotensin type 2 receptor agonist Compound 21 elicits cerebroprotection in endothelin-1 induced ischemic stroke

Evidence indicates that angiotensin II type 2 receptors (AT2R) exert cerebroprotective actions during stroke. A selective non-peptide AT2R agonist, Compound 21 (C21), has been shown to exert beneficial effects in models of cardiac and renal disease, as well as hemorrhagic stroke. Here, we hypothesiz...

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Vydáno v:Neuropharmacology
Hlavní autoři: Joseph, Jason P., Mecca, Adam P., Regenhardt, Robert W., Bennion, Douglas M., Rodríguez, Vermali, Desland, Fiona, Patel, Neal A., Pioquinto, David J., Unger, Thomas, Katovich, Michael J., Muscha Steckelings, U., Sumners, Colin
Médium: Artigo
Jazyk:Inglês
Vydáno: 2014
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7472595/
https://ncbi.nlm.nih.gov/pubmed/24508710
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuropharm.2014.01.044
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