The angiotensin type 2 receptor agonist Compound 21 elicits cerebroprotection in endothelin-1 induced ischemic stroke

Evidence indicates that angiotensin II type 2 receptors (AT2R) exert cerebroprotective actions during stroke. A selective non-peptide AT2R agonist, Compound 21 (C21), has been shown to exert beneficial effects in models of cardiac and renal disease, as well as hemorrhagic stroke. Here, we hypothesiz...

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Detalhes bibliográficos
Publicado no:Neuropharmacology
Main Authors: Joseph, Jason P., Mecca, Adam P., Regenhardt, Robert W., Bennion, Douglas M., Rodríguez, Vermali, Desland, Fiona, Patel, Neal A., Pioquinto, David J., Unger, Thomas, Katovich, Michael J., Muscha Steckelings, U., Sumners, Colin
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7472595/
https://ncbi.nlm.nih.gov/pubmed/24508710
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuropharm.2014.01.044
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