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Site-Specific Resolution of Anionic Residues in Proteins Using Solid-State NMR Spectroscopy
NMR spectroscopy is commonly used to infer site-specific acid dissociation constants (pK(a)) since the chemical shift is sensitive to the protonation state. Methods that probe atoms nearest to the functional groups involved in acid/base chemistry are the most sensitive for determining the protonatio...
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| Published in: | J Biomol NMR |
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| Main Authors: | , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
2020
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7472563/ https://ncbi.nlm.nih.gov/pubmed/32514875 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10858-020-00323-z |
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