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Site-Specific Resolution of Anionic Residues in Proteins Using Solid-State NMR Spectroscopy

NMR spectroscopy is commonly used to infer site-specific acid dissociation constants (pK(a)) since the chemical shift is sensitive to the protonation state. Methods that probe atoms nearest to the functional groups involved in acid/base chemistry are the most sensitive for determining the protonatio...

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Detalhes bibliográficos
Publicado no:J Biomol NMR
Main Authors: Li, Jianping, Sae Her, Ampon, Traaseth, Nathaniel J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7472563/
https://ncbi.nlm.nih.gov/pubmed/32514875
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10858-020-00323-z
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