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Emodin alleviates gemcitabine resistance in pancreatic cancer by inhibiting MDR1/P-glycoprotein and MRPs expression

Gemcitabine is a gold standard chemotherapeutic agent for pancreatic cancer. However, gemcitabine has limited effectiveness due to the short-term development of chemoresistance. Emodin, a natural anthraquinone derivative isolated from the roots of rheumatic palm leaves prevents immunosuppression and...

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Vydáno v:Oncol Lett
Hlavní autoři: Guo, Hongchun, Liu, Feng, Yang, Shuguang, Xue, Tao
Médium: Artigo
Jazyk:Inglês
Vydáno: D.A. Spandidos 2020
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7471752/
https://ncbi.nlm.nih.gov/pubmed/32934734
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ol.2020.12030
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