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Protein QTL analysis of IGF-I and its binding proteins provides insights into growth biology

The growth hormone and insulin-like growth factor (IGF) system is integral to human growth. Genome-wide association studies (GWAS) have identified variants associated with height and located near the genes in this pathway. However, mechanisms underlying these genetic associations are not understood....

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Hum Mol Genet
Hauptverfasser: Bartell, Eric, Fujimoto, Masanobu, Khoury, Jane C, Khoury, Philip R, Vedantam, Sailaja, Astley, Christina M, Hirschhorn, Joel N, Dauber, Andrew
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7471503/
https://ncbi.nlm.nih.gov/pubmed/32484228
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddaa103
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