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RepSox, a small molecule inhibitor of the TGFβ receptor, induces brown adipogenesis and browning of white adipocytes

Unlike white adipose tissue (WAT), brown adipose tissue (BAT) is mainly responsible for energy expenditure via thermogenesis by uncoupling the respiratory chain. Promoting the differentiation of brown fat precursor cells and the browning of white fat have become a research hotspot for the treatment...

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Bibliographic Details
Published in:Acta Pharmacol Sin
Main Authors: Tu, Wan-zhi, Fu, Yan-bin, Xie, Xin
Format: Artigo
Language:Inglês
Published: Nature Publishing Group UK 2019
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7471457/
https://ncbi.nlm.nih.gov/pubmed/31235818
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41401-019-0264-2
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