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Combination of carbon-ion beam and dual tyrosine kinase inhibitor, lapatinib, effectively destroys HER2 positive breast cancer stem-like cells

To investigate whether carbon-ion beam alone, or in combination with lapatinib, has a beneficial effect in targeting HER2-positive breast cancer stem-like cells (CSCs) compared to that of X-rays, human breast CSCs derived from BT474 and SKBR3 cell lines were treated with a carbon-ion beam or X-rays...

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Publicat a:Am J Cancer Res
Autors principals: Sai, Sei, Kim, Eun Ho, Vares, Guillaume, Suzuki, Masao, Yu, Dong, Horimoto, Yoshiya, Hayashi, Mitsuhiro
Format: Artigo
Idioma:Inglês
Publicat: e-Century Publishing Corporation 2020
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7471364/
https://ncbi.nlm.nih.gov/pubmed/32905515
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