Metformin decreases bacterial trimethylamine production and trimethylamine N-oxide levels in db/db mice

The current study aimed to explore whether metformin, the most widely prescribed oral medication for the treatment of type 2 diabetes, alters plasma levels of cardiometabolic disease-related metabolite trimethylamine N-oxide (TMAO) in db/db mice with type 2 diabetes. TMAO plasma concentration was up...

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Pubblicato in:Sci Rep
Autori principali: Kuka, Janis, Videja, Melita, Makrecka-Kuka, Marina, Liepins, Janis, Grinberga, Solveiga, Sevostjanovs, Eduards, Vilks, Karlis, Liepinsh, Edgars, Dambrova, Maija
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2020
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7471276/
https://ncbi.nlm.nih.gov/pubmed/32884086
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-71470-4
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