Effect of genetic variation in Notch regulator DTX1 on SCLC prognosis compared with the effect on NSCLC prongosis

Deltex‐1 (DTX1) is a negative regulator of the Notch signaling pathway. Here, we investigated the clinical effect of DTX1 rs1732786A > G, which is associated with better prognosis in patients with early‐stage non‐small cell lung cancer (NSCLC), in 261 patients with small cell lung cancer (SCLC)....

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Publicat a:Thorac Cancer
Autors principals: Yoo, Seung Soo, Lee, Jang Hyuck, Hong, Mi Jeong, Choi, Jin Eun, Kang, Hyo‐Gyoung, Do, Sook Kyung, Kim, Ji Hyun, Baek, Sun Ah, Choi, Sun Ha, Lee, Won Kee, Lee, Yong Hoon, Seo, Hyewon, Lee, Jaehee, Lee, Shin Yup, Cha, Seung Ick, Kim, Chang Ho, Park, Jae Yong
Format: Artigo
Idioma:Inglês
Publicat: John Wiley & Sons Australia, Ltd 2020
Matèries:
Brief Reports
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7471053/
https://ncbi.nlm.nih.gov/pubmed/32700476
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/1759-7714.13566
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