Effect of genetic variation in Notch regulator DTX1 on SCLC prognosis compared with the effect on NSCLC prongosis

Deltex‐1 (DTX1) is a negative regulator of the Notch signaling pathway. Here, we investigated the clinical effect of DTX1 rs1732786A > G, which is associated with better prognosis in patients with early‐stage non‐small cell lung cancer (NSCLC), in 261 patients with small cell lung cancer (SCLC)....

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Detalhes bibliográficos
Main Authors: Seung Soo Yoo, Jang Hyuck Lee, Mi Jeong Hong, Jin Eun Choi, Hyo‐Gyoung Kang, Sook Kyung Do, Ji Hyun Kim, Sun Ah Baek, Sun Ha Choi, Won Kee Lee, Yong Hoon Lee, Hyewon Seo, Jaehee Lee, Shin Yup Lee, Seung Ick Cha, Chang Ho Kim, Jae Yong Park
Formato: Artigo
Idioma:Inglês
Publicado em: Wiley 2020-09-01
Colecção:Thoracic Cancer
Assuntos:
DTX1
response
rs1732786
SCLC
survival
Acesso em linha:https://doi.org/10.1111/1759-7714.13566
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