Transcriptome-wide stability analysis uncovers LARP4-mediated NFκB1 mRNA stabilization during T cell activation

T cell activation is a well-established model for studying cellular responses to exogenous stimulation. Motivated by our previous finding that intron retention (IR) could lead to transcript instability, in this study, we performed BruChase-Seq to experimentally monitor the expression dynamics of nas...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: Tian, Yi, Zeng, Zhouhao, Li, Xiang, Wang, Yiyin, Chen, Runsen, Mattijssen, Sandy, Gaidamakov, Sergei, Wu, Yuzhang, Maraia, Richard J, Peng, Weiqun, Zhu, Jun
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2020
Assuntos:
RNA and RNA-protein complexes
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7470963/
https://ncbi.nlm.nih.gov/pubmed/32735645
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkaa643
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