Poly(A) binding KPAF4/5 complex stabilizes kinetoplast mRNAs in Trypanosoma brucei

In Trypanosoma brucei, mitochondrial pre-mRNAs undergo 3′-5′ exonucleolytic processing, 3′ adenylation and uridylation, 5′ pyrophosphate removal, and, often, U-insertion/deletion editing. The 3′ modifications are modulated by pentatricopeptide repeat (PPR) Kinetoplast Polyadenylation Factors (KPAFs)...

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Detalles Bibliográficos
Publicado en:Nucleic Acids Res
Main Authors: Aphasizheva, Inna, Yu, Tian, Suematsu, Takuma, Liu, Qiushi, Mesitov, Mikhail V, Yu, Clinton, Huang, Lan, Zhang, Liye, Aphasizhev, Ruslan
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2020
Assuntos:
RNA and RNA-protein complexes
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7470953/
https://ncbi.nlm.nih.gov/pubmed/32614436
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkaa575
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