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Kinetic and Spectroscopic Characterization of the Catalytic Ternary Complex of Tryptophan 2,3-Dioxygenase

The first step of the kynurenine pathway for L-tryptophan (L-Trp) degradation is catalyzed by heme-dependent dioxygenases, tryptophan 2,3-dioxygenase (TDO) and indoleamine 2,3-dioxygenase. In this work, we employed stopped-flow optical absorption spectroscopy to study the kinetic behavior of the Mic...

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Bibliografski detalji
Izdano u:Biochemistry
Glavni autori: Geng, Jiafeng, Weitz, Andrew C., Dornevil, Kednerlin, Hendrich, Michael P., Liu, Aimin
Format: Artigo
Jezik:Inglês
Izdano: 2020
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7470927/
https://ncbi.nlm.nih.gov/pubmed/32659080
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.0c00179
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