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HDAC6-selective inhibitors decrease nerve-injury and inflammation-associated mechanical hypersensitivity in mice

BACKGROUND: HDAC6 is a class IIB histone deacetylase expressed at many levels of the nociceptive pathway. This study tested the ability of novel and selective HDAC6 inhibitors to alleviate sensory hypersensitivity behaviors in mouse models of peripheral nerve injury and peripheral inflammation. METH...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Psychopharmacology (Berl)
मुख्य लेखकों: Sakloth, Farhana, Manouras, Lefteris, Avrampou, Kleopatra, Mitsi, Vasiliki, Serafini, Randal A, Pryce, Kerri D, Cogliani, Valeria, Berton, Olivier, Jarpe, Matthew, Zachariou, Venetia
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: 2020
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC7470631/
https://ncbi.nlm.nih.gov/pubmed/32388618
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00213-020-05525-9
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