HDAC6-selective inhibitors decrease nerve-injury and inflammation-associated mechanical hypersensitivity in mice

BACKGROUND: HDAC6 is a class IIB histone deacetylase expressed at many levels of the nociceptive pathway. This study tested the ability of novel and selective HDAC6 inhibitors to alleviate sensory hypersensitivity behaviors in mouse models of peripheral nerve injury and peripheral inflammation. METH...

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Detaylı Bibliyografya
Yayımlandı:Psychopharmacology (Berl)
Asıl Yazarlar: Sakloth, Farhana, Manouras, Lefteris, Avrampou, Kleopatra, Mitsi, Vasiliki, Serafini, Randal A, Pryce, Kerri D, Cogliani, Valeria, Berton, Olivier, Jarpe, Matthew, Zachariou, Venetia
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2020
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7470631/
https://ncbi.nlm.nih.gov/pubmed/32388618
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00213-020-05525-9
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