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A type IV collagenase inhibitor, N-hydroxy-3-phenyl-2-(4-phenylbenzenesulfonamido) propanamide (BiPS), suppresses skin injury induced by sulfur mustard

Sulfur mustard (SM) is a highly toxic blistering agent thought to mediate its action, in part, by activating matrix metalloproteinases (MMPs) in the skin and disrupting components of the basement membrane zone (BMZ). Type IV collagenases (MMP-9) degrade type IV collagen in the skin, a major componen...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Toxicol Appl Pharmacol
Päätekijät: Chang, Yoke-Chen, Hahn, Rita A, Gordon, Marion K, Laskin, Jeffrey D, Gerecke, Donald R
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2020
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC7470515/
https://ncbi.nlm.nih.gov/pubmed/32479919
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.taap.2020.115078
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