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Advances in synthetic lethality for cancer therapy: cellular mechanism and clinical translation
Synthetic lethality is a lethal phenomenon in which the occurrence of a single genetic event is tolerable for cell survival, whereas the co-occurrence of multiple genetic events results in cell death. The main obstacle for synthetic lethality lies in the tumor biology heterogeneity and complexity, t...
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| 出版年: | J Hematol Oncol |
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| 主要な著者: | , , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
BioMed Central
2020
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7470446/ https://ncbi.nlm.nih.gov/pubmed/32883316 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13045-020-00956-5 |
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