Pharmacologic fibroblast reprogramming into photoreceptors restores vision

Photoreceptor loss is the final common endpoint in most retinopathies that lead to irreversible blindness, and there are no effective treatments to restore vision(1,2). Chemical reprogramming of fibroblasts offers an opportunity to reverse vision loss; however, the generation of sensory neuronal sub...

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Udgivet i:Nature
Main Authors: Mahato, Biraj, Kaya, Koray Dogan, Fan, Yan, Sumien, Nathalie, Shetty, Ritu A., Zhang, Wei, Davis, Delaney, Mock, Thomas, Batabyal, Subrata, Ni, Aiguo, Mohanty, Samarendra, Han, Zongchao, Farjo, Rafal, Forster, Michael J., Swaroop, Anand, Chavala, Sai H.
Format: Artigo
Sprog:Inglês
Udgivet: 2020
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7469946/
https://ncbi.nlm.nih.gov/pubmed/32376950
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41586-020-2201-4
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