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Deep learning for inferring transcription factor binding sites

Deep learning is a powerful tool for predicting transcription factor binding sites from DNA sequence. Despite their high predictive accuracy, there are no guarantees that a high-performing deep learning model will learn causal sequence-function relationships. Thus a move beyond performance compariso...

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Détails bibliographiques
Publié dans:Curr Opin Syst Biol
Auteurs principaux: Koo, Peter K., Ploenzke, Matt
Format: Artigo
Langue:Inglês
Publié: 2020
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7469942/
https://ncbi.nlm.nih.gov/pubmed/32905524
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.coisb.2020.04.001
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