Microfluidic concentration and separation of circulating tumor cell clusters from large blood volumes

Circulating tumor cells (CTCs) are extremely rare in the blood, yet they account for metastasis. Notably, it was reported that CTC clusters (CTCCs) can be 50–100 times more metastatic than single CTCs, making them particularly salient as a liquid biopsy target. Yet they can split apart and are even...

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Publicado en:Lab Chip
Main Authors: Edd, Jon F., Mishra, Avanish, Dubash, Taronish D., Herrera, Stefan, Mohammad, Ridhwan, Kendall Williams, E., Hong, Xin, Mutlu, Baris R., Walsh, John R., de Carvalho, Fernanda Machado, Aldikacti, Berent, Nieman, Linda T., Stott, Shannon L., Kapur, Ravi, Maheswaran, Shyamala, Haber, Daniel A., Toner, Mehmet
Formato: Artigo
Idioma:Inglês
Publicado: 2020
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7469923/
https://ncbi.nlm.nih.gov/pubmed/31934715
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c9lc01122f
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