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Activation of Type 4 Metabotropic Glutamate Receptor Regulates Proliferation and Neuronal Differentiation in a Cultured Rat Retinal Progenitor Cell Through the Suppression of the cAMP/PTEN/AKT Pathway

Retinal progenitor cells (RPCs) remain in the eye throughout life and can be characterized by their ability for self-renewal as well as their specialization into different cell types. A recent study has suggested that metabotropic glutamate receptors (mGluRs) participate in the processes of multiple...

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Pubblicato in:Front Mol Neurosci
Autori principali: Zhang, Zhichao, Liu, Yingfei, Luan, Yan, Zhu, Kun, Hu, Baoqi, Ma, Bo, Chen, Li, Liu, Xuan, Lu, Haixia, Chen, Xinlin, Liu, Yong, Zheng, Xiaoyan
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7469868/
https://ncbi.nlm.nih.gov/pubmed/32973444
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnmol.2020.00141
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