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Activation of Type 4 Metabotropic Glutamate Receptor Attenuates Oxidative Stress-Induced Death of Neural Stem Cells with Inhibition of JNK and p38 MAPK Signaling

Promoting both endogenous and exogenous neural stem cells' (NSCs) survival in the hostile host environments is essential to cell replacement therapy for central nervous system (CNS) disorders. Type 4 metabotropic glutamate receptor (mGluR4), one of the members of mGluRs, has been shown to prote...

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Bibliografske podrobnosti
izdano v:Stem Cells Dev
Main Authors: Zhang, Zhichao, Ma, Wen, Wang, Li, Gong, Hanshi, Tian, Yumei, Zhang, Jianshui, Liu, Jianxin, Lu, Haixia, Chen, Xinlin, Liu, Yong
Format: Artigo
Jezik:Inglês
Izdano: Mary Ann Liebert, Inc. 2015
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4652160/
https://ncbi.nlm.nih.gov/pubmed/26176363
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/scd.2015.0067
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