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Roles of the pyroptosis signaling pathway in a sepsis-associated encephalopathy cell model

OBJECTIVES: The inhibition of pyroptosis has a protective effect in sepsis-associated encephalopathy (SAE). However, the mechanisms underlying pyroptosis in SAE remain to be elucidated. METHODS: Here, we investigated the effects of the caspase inhibitors, Belnacasan (Beln) and Wedelolactone (Wede),...

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Detalhes bibliográficos
Publicado no:J Int Med Res
Main Authors: Wang, Yan, Liu, Xueyan, Wang, Qiang, Yang, Xin
Formato: Artigo
Idioma:Inglês
Publicado em: SAGE Publications 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7469743/
https://ncbi.nlm.nih.gov/pubmed/32865056
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/0300060520949767
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